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Keflex can be used as first-line therapy for MRSA infections and is the most prescribed oral cephalosporin medicine. The cephalosporin group of antibiotics. Although side effects from Cephalexin are not common, they can occur. This drug may cause false results in tests for urine sugar. The infection. Antibiotics, although some side effects can be serious. Cephalexin is used to treat a wide variety of bacterial infections. Keflex may not be well tolerated by all patients and a thorough medical history is recommended prior to prescribing this medication. The medication too early may allow bacteria to continue to grow resulting in a relapse of the infection.