This medication rarely may cause mood or behavior changes, such as phenytoin. The usefulness of Topamax in the acute treatment of migraine headaches in adults. Clinical trials found that patients receiving the recommended daily dose of Topamax experienced a significant reduction in monthly migraine attacks, compared with placebo. Topiramate has been approved for migraine prophylaxis in many countries worldwide. Topiramate is an anticonvulsant used with other medicines to control certain types of seizures in the treatment of epilepsy.
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