In patients with symptoms of gastro-esophageal reflux disease. If taken on an empty stomach at least one hour before meals and at the same time every day. When you buy Nexium from the merchants listed on our website, all orders are confidential. Nexium is used to treat and prevent stomach and intestinal ulcers, damage to the gastrointestinal tract caused by stomach acid or infection. There are no restrictions on food, beverages, or activities while taking Nexium, unless otherwise directed by your doctor. Nexium is used to treat the infection that causes ulcers occurring just beyond the exit from the stomach.