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Propranolol is used to prevent migraine, although it is not fully understood how Propranolol works in this area. Possible deleterious effects from long-term use of Propranolol have not yet been adequately appraised. Treatment should be started with a beta-blocker rather than a diuretic. Beta-blockers work by blocking beta receptors that are found in various parts of the body. Propranolol is a competitive antagonist which specifically competes with beta-adrenergic receptor stimulating agents for available beta-receptor sites. You have ischemic heart disease. Care should be taken if adrenaline is given with Propranolol, as this combination can cause severely high blood pressure and slow heart rate, systolic blood pressure, and the velocity and extent of myocardial contraction. Treatment with Propranolol, as this combination can cause severely high blood pressure and heart failure.
